Lyvgen is an innovative biotech company focused on developing novel therapies for cancer. Its proprietary xLinkAb functional platform generated agonistic antibodies with tumor-localized immunostimulatory activities by balancing multiple functions of candidate antibodies, which has helped to generate a number of drug candidates, including LVGN7409 (CD40 agonist mAb) and LVGN6051 (4-1BB agonist mAb), presently in clinical development. The phase 1 clinical trial of LVGN7409 has been advanced in China and the United States with preliminary clinical breakthrough safety and activity data. LVGN6051 monotherapy has demonstrated safety and activity and is being tested in a phase 1b /2 trial in the United States with pembrolizumab in adults with advanced tumors. LVGN6051 is also in Phase 2 clinical trial in China in combination with small molecule inhibitors of vascular endothelial growth factor receptor.
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Janice Marie McCourt
Chief Business Officer