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      • Pipeline
      • xLink MAb platform
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    • Patient 
      • Cancer Immunotherapy
      • LVGN6051
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  • Home
  • About us 
    • Management
    • Living Innovation
    • Company presentation
  • Science 
    • Pipeline
    • xLink MAb platform
    • xLink BsAb platform
    • xLink MsAb platform
    • Publications
  • Patient 
    • Cancer Immunotherapy
    • LVGN6051
    • LVGN7409
    • LVGN3616
    • Resources
  • News 
    • News
    • Company presentation
  • Partners 
    • Careers
    • Collaboration
    • Contact us
  • …  
    • Home
    • About us 
      • Management
      • Living Innovation
      • Company presentation
    • Science 
      • Pipeline
      • xLink MAb platform
      • xLink BsAb platform
      • xLink MsAb platform
      • Publications
    • Patient 
      • Cancer Immunotherapy
      • LVGN6051
      • LVGN7409
      • LVGN3616
      • Resources
    • News 
      • News
      • Company presentation
    • Partners 
      • Careers
      • Collaboration
      • Contact us
  • English 
    • English
    • 中文
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  • Immune-oncology Agonistic Antibodies

    Cross-linking (xLinkTM)Synthetic Biology

    Tumor-targeted Immune Activation

  • Clinical Development Candidates

    LVGN6051

    Next generation CD137/4-1BB agonistic monoclonal antibody

    LVGN6051 is designed to stimulate the proliferation and cytotoxicity of antitumor immune cells. Optimal efficacy and safety profile are achieved by the crosslinking dependent CD137 agonistic activity through FcγRIIB.

     

     

    LVGN7409

    Next generation CD40 agonistic monoclonal antibody

    CD40 activation by LVGN7409 promotes tumor antigen presentation and induction of cancer-fighting T cells, and "warm up" the immune-"cold" tumor microenvironment. Unique structure and functionality of LVGN7409 permits its higher tolerable dosage and broader clinical utility.

     

     

    LVGN3616

    Proprietary PD-1 blocking monoclonal antibody

    LVGN3616 blocks PD-1 pathway to unleash the "brake" of the immune responses against cancer.

     

  • Lyvgen xLinkAb platform

    xLinkAb Avidity Cross-linking Synthetic Biology

    xLinkMAb

    • Cross-linking monoclonal antibodies
    • Target activation dependent on FcγRIIB engagement

    xLinkBsAb

    • Cross-linking dependent bi-specific antibodies
    • Target activation dependent on binding to another antigen
     
     

    xLinkMsAb

    • Cross-linking multi-specific antibodies
    • New generation CD3 T cell engager with co-stimulation
    • IgG-like design
  • Lyvgen Shanghai

    Suite 317, Building 1, 351 Guoshoujing Road

    Lyvgen Suzhou

    Room 137, Building C36, 188 Dongping Street

    Inquiries

     

    General ------------------------------ ---Business Development----------------------------Employment--------------------------------------Clinical

    info@lyvgen.com  -----------------1 bd@lyvgen.com                  ------------ -----        careers@lyvgen.com    ------------------      clinical@lyvgen.com

     

    Phone +86 021-50663350

    Contact us on LinkedIn

    Copyright © 2022 LYVGEN BIOPHARMA. All Rights Reserved. Lyvgen website is designed to provide general information about the subject matter presented. The information presented does not, and is not intended to, provide medical advice.

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Lyvgen Biopharma Website 礼进生物 英文官网
Lyvgen is a biotech company focused on developing novel therapies for cancer. Lyvgen’s xLinkAb™ functional platform creates agonist antibodies (Abs) with tumor-localized immunostimulatory activities by balancing multiple functions of candidate Abs.
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